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WebCephalosporin MIC creep among gonococci: Time for a pharmacodynamic rethink? ... Dive into the research topics of 'Cephalosporin MIC creep among gonococci: Time … WebMay 3, 2024 · Cephalosporin MIC creep among gonococci: time for a pharmacodynamic rethink? J Antimicrob Chemother. 2010 Oct;65(10):2141-8. doi: 10.1093/jac/dkq289. Epub … 3a in url meaning WebCephalosporin MIC creep among gonococci: time for a pharmacodynamic rethink? J Antimicrob Chemother 2010 ; 65 : 2141 – 48 . OpenUrl Abstract / FREE Full Text WebAug 6, 2010 · Europe PMC is an archive of life sciences journal literature. axis companion app push notifications WebJun 17, 2015 · The MIC 90 of ceftriaxone increased 2-fold from 0.06 to 0.12 mg/L compared with a previous report from the mid-2000s. 2 In infections caused by gonococci with a ceftriaxone MIC of 0.12 mg/L, even when 1 g of ceftriaxone is administered, the time period that the concentration of free ceftriaxone exceeds the MIC (fT >MIC) may be <20 h in the ... WebPharmacodynamic analysis was complicated by evidence that cephalosporins need a longer period with the free drug level above MIC than the 7-10 h required for penicillin G; … axis companion app not working WebIson CA, Livermore DM. Cephalosporin MIC creep among gonococci: time for a pharmacodynamic rethink? J Antimicrob Chemother 2010; 65: 2141–48. Medical Research Council (NHMRC) Project Grant (APP1025517). We declare that we have no confl icts of interest. Monica M Lahra, Basil Donovan, David M Whiley [email protected]
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WebIson CA, Livermore DM. Cephalosporin MIC creep among gonococci: time for a pharmacodynamic rethink? J Antimicrob Chemother 2010; 65: 2141–48. Medical … WebAug 13, 2024 · Cephalosporin MIC creep among gonococci: time for a pharmacodynamic rethink?. J Agents Chemother. 2010; 65: 2141-2148. ... Cephalosporin MIC creep among gonococci: time for a pharmacodynamic rethink?. J Agents Chemother. 2010; 65: 2141-2148. View in Article Scopus (140) Crossref; Google Scholar; … 3a investieren WebOct 1, 2010 · Pharmacodynamic analysis was complicated by evidence that cephalosporins need a longer period with the free drug level above MIC than the 7-10 h … WebAug 25, 2024 · After reports of clinical isolates with reduced susceptibility to cephalosporins, efforts were made to counter emerging cephalosporin resistance, initially by moving away from oral cefixime to high dose intramuscular ceftriaxone and then by a recommendation to combine this with azithromycin.6 7 Despite these changes, the first … 3a investments ltd WebCephalosporin MIC creep among gonococci: time for a pharmacodynamic rethink?. J Antimicrob Chemother. 2010; 65: 2141-2148. Crossref; PubMed; ... Cephalosporin MIC … WebDec 17, 2024 · Chisholm SA, Mouton JW, Lewis DA, Nichols T, Ison CA, Livermore DM. Cephalosporin MIC creep among gonococci: time for a pharmacodynamic rethink? J … 3a investments WebMay 30, 2016 · Based on pharmacodynamic analyses, the single-dose regimen of 1 g of ceftriaxone could be effective against genital gonorrhoea caused by strains exhibiting MICs up to 0.5 mg/L. 17 Clinical isolates of N. gonorrhoeae with a ceftriaxone MIC of ≥0.5 mg/L are still rare. 9–11 At present, this ceftriaxone regimen could be effective against ...
WebDownload Table Weighted a MIC distributions for gonococci by year from publication: Cephalosporin MIC creep among gonococci: Time for a pharmacodynamic rethink? … WebMay 6, 2014 · Chisholm et al. suggest that such a policy has led to a progressive loss of treatments for Neisseria gonorrhoea – sulphonamides, penicillin and quinolones, with evidence that cephalosporin MICs are now increasing 39. Whilst antibiotic stewardship programmes have been shown to be beneficial, it is unclear which particular intervention … 3a investment WebDec 31, 2009 · Cephalosporin MIC creep among gonococci: time for a pharmacodynamic rethink? ... We examined cephalosporin MIC trends for Neisseria gonorrhoeae in the UK and undertook pharmacodynamic analyses to predict efficacy against strains with raised MICs. ... There was a progressive emergence of small … 3a investors WebCephalosporin MIC creep among gonococci: time for a pharmacodynamic rethink? J Antimicrob Chemother. 2010; 65(10):2141-8 (ISSN: 1460-2091) Chisholm SA; Mouton … WebJan 9, 2013 · Pharmacodynamic analysis was complicated by evidence that cephalosporins need a longer period with the free drug level above MIC than the 7-10 h required for penicillin G; nevertheless ... 3a investment company act WebPharmacodynamic analysis was complicated by evidence that cephalosporins need a longer period with the free drug level above MIC than the 7–10 h required for penicillin G; nevertheless, pharmacodynamic analyses predict that failures with the standard 400 mg cefixime po and 250 mg ceftriaxone im regimens become likely around the present MIC ...
WebDM. Cephalosporin MIC creep among gonococci: time for a . pharmacodynamic rethink? J Antimicrob Chemother 2010;65:2141–8. ... among gonococci, worldwide, ... axis companion app store WebDec 31, 2009 · Cephalosporin MIC creep among gonococci: time for a pharmacodynamic rethink? ... We examined cephalosporin MIC trends for Neisseria … 3 a investment company act