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Structure and Functions of Aquaporin-4-Based Orthogonal Arrays of Particles?

Structure and Functions of Aquaporin-4-Based Orthogonal Arrays of Particles?

WebMay 15, 2012 · Hinson et al. suggested a unique mechanism for the pathogenesis of neuromyelitis optica (NMO), a neuroinflammatory disease caused by binding of an autoantibody (NMO-IgG) to aquaporin-4 (AQP4) on astrocyte plasma membranes.AQP4 is expressed as long (called M1) and short (called M23) isoforms, the latter forming … WebJan 1, 2011 · 1. Introduction. The scientific histories of the so-called orthogonal (square) arrays (assemblies) of intramembranous particles (OAPs) on the one hand, and that of the aquaporins on the other hand, have different roots: the OAPs were first described in liver cells (Kreutziger, 1968).Staehelin (1972) described OAPs as a third type of gap junctions … astro league of legends WebJan 1, 2011 · Orthogonal arrays or assemblies of intramembranous particles (OAPs) are structures in the membrane of diverse cells which were initially discovered by means of the freeze-fracturing technique. This technique, developed in the 1960s, was important for the acceptance of the fluid mosaic model of the biological membrane.OAPs were first … WebRossi et al (2012) Super-resolution imaging of aquaporin-4 orthogonal arrays of particles in cell membranes. J.Cell Sci. 125 4405 PMID:22718347 Burnette et al (2011) Bleaching/blinking assisted localization microscopy for superresolution imaging using standard fluorescent molecules. Proc.Natl.Acad.Sci.USA. 108 21081 PMID:22167805 … 80 carriage cir stockbridge ga WebAquaporin-4 (AQP4) is the only known aquaporin to show a higher ordering level in the membrane. Tetramers are assembled in supramolecular structures called orthogonal arrays of particles (OAP) , which are stabilized by the interaction between aminoterminal WebDec 31, 2011 · Orthogonal arrays or assemblies of intramembranous particles (OAPs) are structures in the membrane of diverse cells which were initially discovered by means of the freeze-fracturing technique ... astro led sideboard WebFeb 19, 2009 · Neuromyelitis optica (NMO) is an inflammatory autoimmune demyelinating disease of the central nervous system (CNS) which in autoantibodies produced by patients with NMO (NMO-IgG) recognize a glial water channel protein, Aquaporin-4 (AQP4) expressed as two major isoforms, M1- and M23-AQP4, in which the plasma membrane …

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