High affinity copper uptake protein 1-like

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August undefined, 2024

Web7 de mai. de 2024 · Cuprizone administration induces mitochondrial enlargement, severely alters metabolic rates, and impairs oxidative phosphorylation by reducing mitochondrial enzymes that contain copper as a cofactor, such as monoamine oxidase [ 27] and cytochrome c (Cyt c) oxidase [ 28, 29] in the brain of mice. Web30 de mar. de 2024 · Functional assays revealed that it stimulates the initial rate of radiolabeled copper uptake. CTR1 transports copper with high affinity in a time-dependent and saturable manner and is copper-specific. Transport is an energy-independent process and is stimulated by extracellular acidic pH and high K+ …

A re-evaluation of the role of hCTR1, the human high-affinity copper ...

WebProtein High affinity copper uptake protein 1 Gene SLC31A1 Source organism Homo sapiens (Human) go to search UniProt O15431 go to UniProt Experimental structures 3 … Web9 de jun. de 2024 · ATP7A, copper-transporting ATPase 1; ATP7B, copper-transporting ATPase 2; ATOX1, copper transport protein ATOX1; BBB, blood-brain barrier; CCS, copper chaperone for superoxide dismutase; CNS, central nervous system; CP, ceruloplasmin; CTR1, high affinity copper uptake protein 1; CTR2, probable low … grammar is a common one crossword

PET Imaging Radiotracers of Chemokine Receptors

Websible that the fusion of S. cerevisiae Ctr1 and Ctr3-like proteins may be an early event that led to the evolution of high affinity copper transport proteins of other eukaryotes (15, 17). Since most eukaryotic high affinity copper transporters iden-tified to date have strong homology to Ctr3, it is important to WebHuman CTR1 is a high-affinity copper transporter that also mediates the uptake of the anticancer drug cisplatin by largely unknown transport mechanisms. Here we report the 6 … Web21 de abr. de 2011 · COPT7 alone could mediate a high-affinity Cu uptake in the yeast mutant. None of the seven COPTs alone or in cooperation could complement the phenotypes of S. cerevisiae mutants that lacked the transporter genes either for iron uptake or for zinc uptake. china rechargeable hearing aid

Full article: Iron uptake proteins in algae and the role of Iron ...

X-ray structures of the high-affinity copper transporter Ctr1

Webencode a high affinity copper uptake process and was found to be 29% identical at the primary structure level with Ctr1 from yeast. The human protein was, however, substantially smaller than the yeast protein, being composed of 190 amino acids as compared with 406 amino acids (see Fig. 1). hCTR1 is on the WebProtein target information for High affinity copper uptake protein 1 (house mouse). Find diseases associated with this biological target and compounds tested against it in … grammar in use von cambridge university pressWebLOC106138791 high affinity copper uptake protein 1-like [] Gene ID: 106138791, updated on 13-Feb-2024. Summary Other designations. high affinity ... china rechargeable flood light

"Web11 de mai. de 2024 · At physiological pH, NGF peptides bind one equivalent of copper ion with higher affinity of Aβ and lower than hCtr1 peptide fragments. Therefore, in the synaptic cleft, NGF may act as a potential copper chelating molecule, ionophore or chaperone for hCtr1 for metal uptake. " - High affinity copper uptake protein 1-like

High affinity copper uptake protein 1-like

The SLC31 (Ctr) copper transporter family SpringerLink

WebThe affinity measured by Km value for the drugs transported by their corresponding DTs were unified to the unit of micromolar 4. 2D and 3D Structures of Small Molecular Drugs The structures of the small molecular drugs transported by DTs were drawn and were standardized in the .sdf format (both 2D and 3D) 5. Web22 de out. de 2024 · One may speculate about copper speciation and/or mechanisms of copper uptake and release. Apart from trafficking in complex with various neurotransmitters, carrier peptides and proteins, or as part of the protein cargo of extracellular vesicles there is also the potential for copper uptake as a result of …

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WebGene ID: 102804936, updated on 5-Feb-2024. Summary Other designations. high affinity copper uptake protein 1-like Web15 de abr. de 2024 · High affinity copper uptake protein 1 (pig) Protein Target - PubChem Apologies, we are having some trouble retrieving data from our servers...

WebChemokines and chemokine receptors have been recognized as critical signal components that maintain the physiological functions of various cells, particularly the immune cells. The signals of chemokines/chemokine receptors guide various leukocytes to respond to inflammatory reactions and infectious agents. Many chemokine receptors play supportive … Web22 de ago. de 2024 · Crystal structure of the high-affinity copper transporter Ctr1 in complex with Cu (I) PDB DOI: 10.2210/pdb6M98/pdb Classification: TRANSPORT PROTEIN Organism (s): Salmo salar, Escherichia coli Expression System: Komagataella phaffii GS115 Mutation (s): Yes Membrane Protein: Yes PDBTM MemProtMD mpstruc …

Web11 de abr. de 2024 · Several lines of evidence presented here strongly suggest that the first histidine (His43) upstream from TMD1 is absolutely required for the copper transport … Web10 de abr. de 2024 · Abstract Heavy metal contamination impacts plant growth and productivity by causing damage at all levels of plant organization, making it one of the most significant abiotic stressors. This study evaluated the uptake and distribution of cadmium (Cd) and copper (Cu) in Solanum lycopersicum L. and identified the antioxidant enzyme …

Web27 de abr. de 2024 · Multicopper oxidases (MCOs) are blue copper containing proteins and they generally have multiple copper atoms (1 to 6) per molecule [1,2].Diverse enzymes belong to this family of proteins that include laccases, ferroxidases, ascorbate oxidase, bilirubin oxidase and laccase-like MCOs [].MCOs are produced by both prokaryotic as …

Web11 de abr. de 2024 · Several lines of evidence presented here strongly suggest that the first histidine (His43) upstream from TMD1 is absolutely required for the copper transport activity of COPT1 protein. Firstly, deletion of 43 residues, but not 41 residues, of the extracellular N-terminus, completely blocked high affinity copper uptake of COPT1. china rechargeable inspection lightWebCopper uptake transmembrane transporter activity Specific Function High-affinity, saturable copper transporter involved in dietary copper uptake. Pfam Domain Function. … grammar in use upper intermediate pdfWebHigh affinity copper uptake protein 1 is a protein that in humans is encoded by the SLC31A1 gene.[5][6] For faster navigation, this Iframe is preloading the Wikiwand page … grammar is the greatest joy in lifeWeb27 de mar. de 2024 · Copper (Cu) is an essential trace element for growth and development and abnormal Cu levels are associated with anemia, metabolic disease and cancer. … china rechargeable muscle massagerWebHigh affinity copper uptake protein 1: Synonyms: Copper transporter 1; Solute carrier family 31 member 1; hCTR1; Gene Name: SLC31A1: Protein Type: Transporter: … grammar knowledge organiserWeb28 de nov. de 2024 · DOI: 10.3389/fmolb.2024.1055356 Abstract More than a decade ago, studies on cellular cisplatin accumulation via active membrane transport established the role of the high affinity copper uptake protein 1 (CTR1) as a main uptake route besides passive diffusion. grammar jacks copy and pasteWebHigh affinity copper uptake protein 1 Gene SLC31A1 Status UniProtKB reviewed (Swiss-Prot) Organism Homo sapiens (Human) Amino acids 190 Protein existence Evidence at protein level Annotation score 5/5 Entry Feature viewer Publications External links History BLAST Download Add a publication Entry feedback Function grammar in writing definition