Btn3a1-fc
WebJan 15, 2024 · We also show here that surface expression of BTN3A1 by monocytes correlates positively with γδ T cell expansion. Moreover, treatment with BTN3A1-Fc … WebMar 16, 2024 · Shattuck’s bispecific GADLEN compound, which contains heterodimeric BTN2A1 and BTN3A1 extracellular domains fused via an inert Fc linker to an scFv domain targeting CD20 tumor-antigens, demonstrated an ability to rapidly deplete human and cynomolgus B cells in a dose-dependent manner.
Btn3a1-fc
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WebMay 20, 2016 · BTN3A1-Fc enhanced activation of T cells across all subsets measured. (FIG. 3B) In the absence of CD3 engagement, stimulation through BTN3A1 did not alter T cell activation. FIG. 4A-4E. BTN3A1 ectodomain polypeptides induced activation and maturation of dendritic cells (DCs) and monocyte populations. (FIG. 4A) Heat map of MFI … WebBackground: CD277/BTN3A1 Butyrophilin 3A1 (also called BTN3A1) is a 57 kDa type I transmembrane glycoprotein member of the Ig superfamily. It is expressed on a wide …
WebButyrophilin 3A1 (also called BTN3A1) is a 57 kDa type I transmembrane glycoprotein member of the Ig superfamily. It is expressed on a wide variety of immune cells. Similar to BTN3A2 and BTN3A3, BTN3A1 (484 amino … WebAug 1, 2024 · Moreover, treatment with BTN3A1-Fc increased the expansion efficiency of peripheral blood mononuclear cells (PBMCs) from donors harboring γδ T cells with poor expansion capacity. Taken together, the data suggest that the level of BTN3A1 expressed on the surface of monocytes is a useful biomarker for predicting the degree of expansion …
WebButyrophilin subfamily 3 member A1 (BTN3A1) is also known as CD277 and BTF5, which belongs to the immunoglobulin superfamily and contains one B30.2/SPRY domain and … WebThe BTN3A1-has-miR-20b-5p-HCP5 relationship may be the potential interaction mechanism between BC and immune cells. Keywords: breast cancer, differentially expressed mRNA, function and pathway analysis, protein–protein interaction network, mRNA–miRNAs–lncRNA regulation network ... (FC) >1 were selected as the thresholds …
WebAug 21, 2024 · Here, we report that the butyrophilin BTN3A1 inhibits tumor-reactive αβ T cell receptor activation by preventing segregation of N-glycosylated CD45 from the …
WebHuman BTN3A1/2/3 Alexa Fluor® 750-conjugated Antibody Recombinant Monoclonal Antibody. FAB7136S Flow Show Size & Price Human BTN3A1/2/3 Alexa Fluor® 594-conjugated Antibody Recombinant Monoclonal Antibody. FAB7136T Flow Show Size & Price Human BTN3A1/2/3 Alexa Fluor® 350-conjugated Antibody Recombinant … rail route coach yardWebRecombinant Mouse BTN2A2/Butyrophilin 2A2 Protein, CF Cat # 8997-BT Human CD1d Antibody Cat # MAB6979 Recombinant Human CD277/BTN3A1 Fc Chimera Protein, CF … rail route between india and bangladeshWebClone BT3.1 recognizes the human CD277 antigen, a single-pass type I membrane protein, which is also known as butyrophilin subfamily 3 member A1 (BTN3A1). CD277 belongs to the B7 family members and is expressed in various immune cells such as T cells, B cells, monocytes, NK cells, dendritic cells, a subset of stem cells, and endothelial cells. rail rostersWebOct 15, 2024 · Vγ9Vδ2 + T cell-targeted immunotherapy is of interest to harness its MHC-independent cytotoxic potential against a variety of cancers. Recent studies have identified heterodimeric butyrophilin (BTN) 2A1 and BTN3A1 as the molecular entity providing "signal 1" to the Vγ9Vδ2 TCR, but "signal 2" costimulatory requirements remain unclear. rail runabout ticketWebBTN3A1/CD277 Protein, Human (225a.a, HEK293, Fc) is a recombinant human BTN3A1 produced in HEK293 cells, with His tag. BTN3A1 is a member of butyrophilin family [1] . … rail routes in spainWebAug 21, 2024 · We observed that αβ T cells activated in the presence of BTN3A1-Fc proteins (but not PD-L1-Fc) generated CD45-specific peptides approximately double the … rail routes map indiaWebRecombinant Human BTN3A1 protein (Fc Chimera) is a HEK 293 Protein fragment 30 to 254 aa range, > 95% purity, < 1.000 Eu/µg endotoxin level and validated in SDS-PAGE. rail route map of india