3D chromatin connectivity underlies replication origin efficiency …?

3D chromatin connectivity underlies replication origin efficiency …?

WebDec 1, 2024 · INTRODUCTION. Replication origins are fundamental elements for genomic stability, and their precise number, position and regulation in different organisms has … WebSep 1, 2004 · ORCID uses cookies to improve your experience and to help us understand how you use our websites. Learn more about how we use cookies.. Dismiss. We notice … certified plumbing school WebDec 7, 2024 · [Nucleic Acids Research] Researchers analyzed origin activity in mESCs in the absence or presence of mild replicative stress induced by aphidicolin, a DNA … WebNov 28, 2024 · 3D chromatin connectivity underlies replication origin efficiency in mouse embryonic stem cells. Karolina Jodkowska, Vera Pancaldi, ... Genome Integrity, Repair and Replication. Human DNA polymerase α has a strong mutagenic potential at the initial steps of DNA synthesis. certified plumber salary WebJodkowska, Karolina, Vera Pancaldi, Maria Rigau, Ricardo Almeida, José M. Fernández-Justel, Osvaldo Graña-Castro, Sara Rodríguez-Acebes, et al. “3D Chromatin Connectivity Underlies Replication Origin Efficiency in Mouse Embryonic Stem Cells.” WebOct 26, 2005 · DNA replication initiates at discrete origins along eukaryotic chromosomes. However, in most organisms, origin firing is not efficient; a specific origin will fire in some but not all cell cycles. This observation raises the question of how individual origins are selected to fire and whether origin firing is globally coordinated to ensure an even … certified plumber singapore WebDec 7, 2024 · 3D Chromatin Connectivity Underlies Replication Origin Efficiency in Mouse Embryonic Stem Cells Researchers analyzed origin activity in mESCs in the absence or presence of mild replicative stress induced by aphidicolin, a DNA polymerase inhibitor, or by deregulation of origin licensing factor CDC6.

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